Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with an overall 5-year survival rate of 10%.Disease lethality is due to late diagnosis, early metastasis and resistance to therapy, including immunotherapy.PDA creates a robust fibroinflammatory tumor microenvironment that contributes to immunotherapy resistance.While previously consider
The effect of different mix ratios on the mechanical properties of concrete was investigated.The strength Acid Toner and deformation in terms of the strain of normal strength concrete were evaluated under concentric loading.The artificial neural network (ANN) technique was used for predicting the compressive stress and strain at peak stress of conc
Plasmacytoid Dendritic Cells (pDCs) represent a key immune cell in the defense against viruses.Through Facial Toner pattern recognition receptors (PRRs), these cells detect viral pathogen associated molecular patterns (PAMPs) and initiate an Interferon (IFN) response.pDCs produce the antiviral IFNs including the well-studied Type I and the more rec
Abstract Background Schistosomiasis is prevalent in tropical and subtropical areas and rarely reported in developed countries.Schistosomiasis often occurs as a chronic illness, which can cause liver and intestinal damage.Appendicitis is an unusual complication of schistosomiasis.We herein present a case Brake Rotor of acute appendicitis associated